Acitretin for the management of generalized cutaneous lichen planus

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Acitretin for the management of generalized cutaneous lichen planus.

BACKGROUND Lichen planus is an inflammatory disease that affects the skin, the oral mucosa, or both. Generalized cutaneous lichen planus may pose a therapeutic challenge for clinicians if the condition persists or flares after topical or systemic corticosteroid therapy. PURPOSE Acitretin, a systemic retinoid, can be considered a potential second-line treatment for patients with generalized cu...

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Low dose Methotrexate for the treatment of generalized lichen planus

Background: Lichen planus is a common inflammatory disease that can involve the skin, nails, mucous membrane, and hair follicles. There is a long list of topical and systemic therapies for its treatment. Methotrexarte has some characteristics that make it a good choice for generalized lichen planus. Aim: The goal of this study was to assess the effect of low dose methotrexate in generalized lic...

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Disseminated hypertrophic lichen planus: relevant response to acitretin.

Hyperthrofic lichen planus is considered a variant of lichen planus with marked epidermal hyperplasia in response to persistent itch. It is clinically, characterized by symmetric hyperkeratotic plaques, of purplish-grey color, often located in the pretibial region. Intense pruritus, refractoriness to conventional treatments and the possibility of association of the long-term injuries with squam...

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Severe generalized ulcerative lichen planus.

A 67-year-old man was referred to our hospital in March 2000 for evaluation of poikiloderma on the entire body surface. The lesions started as an itching rash on the buttock in 1965 and had gradually spread, especially during summer months. Erosions and/or ulcers had formed on the trunk and limbs a few times per year since 1968. These lesions healed within a month without treatment, leaving eit...

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ژورنال

عنوان ژورنال: Dermatology Online Journal

سال: 2014

ISSN: 1087-2108

DOI: 10.5070/d3209023915